AV-951, Tivozanib | VEGFR,PDGFR, c-Kit Inhibitor | buy from supplier Selleck

Seeded on Tue Feb 7, 2012 9:36 PM EST ()

Tivozanib (AV-951) is an orally bioavailable potent VEGFR-1, 2 and 3, c-Kit and PDGFR inhibitor with IC50 of 0.21, 0.16, 0.24, 1.63 and 1.72 nM, respectively. Order AV-951(Tivozanib) from supplier Selleck for research use only.

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Beta Amyloid 信号通路

Seeded on Tue Feb 7, 2012 9:32 PM EST ()

Inhibitors, Antibodies and siRNAs on Cell Beta Amyloid pathway are available at Selleck. Check A beta signaling reviews and assay information.

beta, amyloid, inhibitor

ATPase 信号通路

Seeded on Tue Feb 7, 2012 9:28 PM EST ()

Inhibitors, Antibodies and siRNAs on Cell ATPase pathway are available at Selleck. Check Adenosinetriphosphatase signaling reviews and assay information.

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Sodium Channel 信号通路

Seeded on Tue Feb 7, 2012 9:25 PM EST ()

Inhibitors, Antibodies and siRNAs on Sodium Channel pathway are available at Selleck. Check Na Channel signaling reviews and assay information.

channel, sodium

Calcium Channel 信号通路

Seeded on Tue Feb 7, 2012 9:22 PM EST ()

Inhibitors, Antibodies and siRNAs on Calcium Channel pathway are available at Selleck. Check Ca Channel signaling reviews and assay information.

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Gamma-Secretase 信号通路

Seeded on Tue Feb 7, 2012 9:15 PM EST ()

Inhibitors, Antibodies and siRNAs targeting Gamma Secretase are available at Selleck. Check Secretase pathway reviews and assay information.

gamma-secretase

Wnt / beta-catenin 信号通路

Seeded on Tue Feb 7, 2012 9:09 PM EST ()

Inhibitors, Antibodies and siRNAs on Wnt pathway are available at Selleck. Check Wnt / beta-catenin reviews and assay information.

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TGF-beta / Smad 信号通路

Seeded on Tue Feb 7, 2012 9:06 PM EST ()

Inhibitors, Antibodies and siRNAs targeting TGF-beta/Smad are available at Selleck. Check TGF-beta pathway reviews and assay information.

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TSU-68, SU6668 | EGFR, PDGFR, FGFR Inhibitor | buy from supplier Selleck

Seeded on Tue Feb 7, 2012 9:01 PM EST ()

TSU-68 (SU6668) is a novel multiple receptor tyrosine kinase inhibitor with IC50 of 2.1 µM, 8 nM and 1.2 µM for VEGF-R1, PDGF-Rβ and FGF-R1, respectively. Order TSU-68 (SU6668) from supplier Selleck for research use only.

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Vatalanib, PTK787 | VEGFR, c-Kit Inhibitor | buy from supplier Selleck

Seeded on Tue Feb 7, 2012 8:58 PM EST ()

Vatalanib (PTK787) is a novel VEGFR and c-Kit tyrosine kinases and angiogenesis inhibitor with IC50 of 0.037, 0.077, 0.27 and 0.73 μM for KDR, Flt-1, Flk and c-Kit, respectively. Order Vatalanib (PTK787) from supplier Selleck for research use only.

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SB-525334 | ALK Inhibitor | buy from supplier Selleck

Seeded on Tue Feb 7, 2012 8:48 PM EST ()

SB 525334 is a selective inhibitor of transforming growth factor-β receptor I (ALK5, TGF-βRI) (IC50 = 14.3 nM). Order SB 525334 from supplier Selleck for research use only.

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SB590885 | B-Raf Inhibitor | buy from supplier Selleck

Seeded on Tue Feb 7, 2012 8:40 PM EST ()

SB590885 is a novel, potent and selective small molecule B-Raf kinase inhibitor with Ki app of 0.16 ± 0.03 nM. ★ Order SB590885 from supplier Selleck for research use only.

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SB939 | HDAC Inhibitor | buy from supplier Selleck

Seeded on Tue Feb 7, 2012 8:31 PM EST ()

SB939 is a novel potent and orally active histone deacetylase inhibitor with an IC50 of 52 nM for HDAC1 and a GI50 of 0.56 μM for Colo205. Order from supplier Selleck for research use only.

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Vicriviroc | CCR5 Inhibitor | buy from supplier Selleck

Seeded on Tue Feb 7, 2012 8:29 PM EST ()

Vicriviroc is a CCR5(cellular coreceptor 5) inhibitor, in vitro activity against HIV (IC9013 nM). Order Vicriviroc from supplier Selleck for research use only.

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Semagacestat, LY450139 | γ-secretase Inhibitor | buy from supplier Selleck

Seeded on Tue Feb 7, 2012 8:23 PM EST ()

Semagacestat (LY450139) is a γ-secretase blocker with an IC50 of 15 nM. Order Semagacestat (LY450139) from supplier Selleck for research use only.

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SGI-1776 | Pim Inhibitor | buy from supplier Selleck

Seeded on Tue Feb 7, 2012 8:20 PM EST ()

SGI-1776 is a selective Pim family kinase inhibitor with IC50 of 7 ± 1.8, 363 ± 27.6 and 69 ± 9.2 nM for Pim-1, Pim-2 and Pim-3 ★ Order SGI-1776 from supplier Selleck for research use only.

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VX-222 | HCV Protease Inhibitor | buy from supplier Selleck

Seeded on Tue Feb 7, 2012 8:16 PM EST ()

VX-222 is a small molecule non-nucleoside inhibitor of HCV NS5B polymerase that is being investigated for the treatment of hepatitis C virus infection. Order VX-222 from supplier Selleck for research use only.

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SGX-523 | c-Met/HGFR Inhibitor | buy from supplier Selleck

Seeded on Tue Feb 7, 2012 8:11 PM EST ()

SGX-523 is an exquisitely selective, ATP-competitive MET receptor tyrosine kinase inhibitor with IC50 of 4 nM for the inhibition of HGFR. Order SGX-523 from supplier Selleck for research use only.

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SNS-314 | Aurora Inhibitor | buy from supplier Selleck

Seeded on Tue Feb 7, 2012 8:06 PM EST ()

SNS-314 is an Inhibitor of Aurora kinases A(IC50=9.0nM),B(IC50=31nM) and C(IC50=3.4nM). Order SNS-314 from supplier Selleck for research use only.

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SP600125 | JNK Inhibitor | buy from supplier Selleck

Seeded on Tue Feb 7, 2012 7:59 PM EST ()

SP600125 is a JNK inhibitor with IC50=40 nM for JNK-1 and JNK-2 and 90 nM for JNK-3. Order SP600125 from supplier Selleck for research use only.

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SRT1720 | PARP Inhibitor | buy from supplier Selleck

Seeded on Tue Feb 7, 2012 6:25 AM EST ()

A selective activator of human SIRT1. Order SRT1720 from supplier Selleck for research use only.

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Staurosporine | PKC Inhibitor | buy from supplier Selleck

Seeded on Tue Feb 7, 2012 6:19 AM EST ()

Staurosporine is a prototypical potent ATP-competitive kinase inhibitor with IC50 of 0.7, 7, 8.5, 6, 20 nM for PKC, PKA,PKG, p60v-src tyrosine protein kinase, CaM kinase II, respectively. Order Staurosporine from supplier Selleck for research use only.

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STF-62247 | buy from supplier Selleck

Seeded on Tue Feb 7, 2012 6:10 AM EST ()

TSTF-62247 selectively causes lethality in RCC cells that have lost the VHL tumor suppressor activity (IC50 = 625 μM). Order STF-62247 from supplier Selleck for research use only.

stf-62247